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In parallel, the liver-expressed enzyme tryptophan 2,3-dioxygenase (TDO2) catalyzes the same initial step of tryptophan catabolism under homeostatic conditions and is primarily regulated by glucocorticoids and tryptophan levels 43,51

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To view a copy of this licence, visit About this article Cite this article Overgaard, R.V., Navarria, A., Ingwersen, S.H