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Both CD8 and CD4 T cell subsets declined in aCD3-treated mice, while the relative proportion of FoxP3 regulatory T cells within the CD4 T cell compartment increased, consistent with the known immunomodulatory actions of aCD3 (Fig

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Evidence-based lifestyle modificationincluding 510% body weight loss, Mediterranean-style diet, and 150 minutes weekly of moderate exerciseremains the cornerstone of NAFLD management

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Results were published in The Lancet

and the The Centre for Phenogenomics for plasma analysis