In Cryptococcus neoformans , chromosomal aneuploidy and hypermutations drive target overexpression and efflux (Iyer et al., 2021
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6.3 The kynurenine pathway: an interactive mechanism linking gut microbiota, immunity, and neurotransmitters Specific neurotransmitters, such as GABA, dopamine, glutamate, and serotonin (5-HT), are derived from precursors tyrosine and tryptophan, which are transported across the BBB into the CNS and subsequently converted into neurotransmitters (213)
doi: 10.1016/j.bbi.2012.02.008 424 BalinasCEaton-FitchNMaksoudRStainesDMarshall-GradisnikS