3.) Clinician consideration Studies show that clinician comfort and training strongly influence whether evidence-based obesity treatments are offered
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N Engl J Med 391(13):11931205 Li M, Lin H, Yang Q, Zhang X, Zhou Q, Shi J et al (2025) Glucagon-like peptide-1 receptor agonists for the treatment of obstructive sleep apnea: a meta-analysis
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The goal isnt to eliminate the enzyme but to ensure it doesnt degrade GLP-1 so rapidly that the hormone cant execute its metabolic coordination functions effectively
These additional effects could also be due to GLP-1 analogs higher plasma concentrations and prolonged persistence in the body over natural GLP-1 receptoractivating molecules, according to Yuan