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At the epithelial level, the drug-induced expansion of butyrate-producing bacteria becomes structurally pivotal: butyrate serves as the primary fuel for colonocytes, stimulates tight junction assembly (upregulating proteins such as occluding and zonula occludens-1 [ZO-1]), and induces mucin production from goblet cells, thereby thickening the protective mucus layer
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While glutathione skin-lightening creams and injections are available, these uses are more common in Asia, and there are safety concerns with high-dose glutathione for cosmetic purposes
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Christensen JJ, Osnes LT, Halvorsen B, Retterstol K, Bogsrud MP, Wium C, Svilaas A, Narverud I, Ulven SM, Aukrust P, Holven KB
