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Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients

The pivotal STEP 1 trial (Wilding et al., 2021) and subsequent safety analyses provide the evidence base for these observations

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Free Radic Biol Med 68:2234 Seet RC, Lee CYJ, Lim EC, Quek AM, Huang H, Huang SH, Halliwell B (2011) Oral zinc supplementation does not improve oxidative stress or vascular function in patients with type 2 diabetes with normal zinc levels