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Effects of hepatitis B virus, alcohol drinking, cigarette smoking and familial tendency on hepatocellular carcinoma

doi: 10.1038/s41574-019-0176-8 2

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6 Since the IGF-1R signaling pathway is critical for the development, maintenance, and survival of cancers, many small molecule compounds and antibodies targeting IGF-1R have been developed

In a nondiabetic glomerular injury model, alogliptin (20 mg/kg/day), anagliptin (300 mg/kg/day), or exendin-4 (10 mg/kg) significantly reduced infiltration of CD68-positive inflammatory macrophages in the kidney [107]