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The lifespan of the neonatal RBC ranges between 60 and 90 days, while that of preterm infants are even shorter at 3550 days (66)

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For example, SGLT2i should be prioritized in patients with HF or CKD, while GLP-1 RAs may be more favorable in patients with higher ASCVD risk or obesity

Hsd11b1 and Hsd11b2 cooperatively regulate intracellular glucocorticoid activity: Hsd11b1 catalyzes the activation of inactive cortisone to cortisol, whereas Hsd11b2 inactivates cortisol by converting it to cortisone