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The majority of the reported events occurred in patients who experienced gastrointestinal reactions leading to dehydration such as nausea, vomiting, or diarrhea

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Brain Histology In the assessment of the occlusion-like syndrome in isoprenaline-treated rats sacrificed at 30 min after isoprenaline 75 mg/kg s.c

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However, in a recent comprehensive and thoughtful review, Smith and Refsum argue that there is indeed a benefit to lowering homocysteine with B vitamin supplements, but that the efficacy depends on the characteristics of those being treated before supplementation is initiated (48)

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