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2.2.5 Pyocyanin-regulated cytokine expression Pyocyanin-mediated oxidative stress has been shown to trigger the expression of pro-inflammatory cytokines through the activation of various host signaling pathways, among others, NF-B and MAPK (93, 146148)

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Tamura H, Takasaki A, Miwa I, Taniguchi K, Maekawa R, Asada H, Taketani T, Matsuoka A, Yamagata Y, Shimamura K, et al: Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate

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