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This excessive connectivity leads to chronic mitochondrial Ca 2+ overload, triggering reactive oxygen species (ROS) production and hepatic UPR activation (Jelenik et al., 2017)

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They form mixed micelles with lipids in the intestinal lumen, facilitating the solubilization and transmembrane transport of fatty acids, monoglycerides, and cholesterol ( Microbial modification of bile acids is an important component of gut-liver axis function

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