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Prescribers are advised to: Review eGFR before initiating treatment and consult the relevant SmPC for renal-specific guidance Monitor renal function periodically during therapy, particularly in those with CKD, risk factors, or on nephroactive medicines Counsel patients on adequate hydration, especially during periods of illness or reduced oral intake Patients should always ensure their prescriber is aware of any kidney condition before starting any weight loss medication
Lower persistence on therapy limits prescription continuity and restrains sustained market growth
Comparing Onset Speed: Retatrutide vs Other GLP-1 Medications Understanding how Retatrutide compares to other medications in its class helps contextualize its onset timeline and set appropriate expectations
For example, some people may feel judged for using GLP-1 medications, or worry that others will see medicated weight loss as the easy way out. Over time, this shame or self-consciousness could affect a persons confidence and mood
