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This worsens electron leakage and ROS production, triggers apoptosis and inflammation, and accelerates hepatocyte dysfunction and fibrosis in CRHM syndrome

Neuropharmacology 2012

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For example, liraglutide and semaglutide have been shown to remodel the gut microbiota toward SCFA-producing and mucus-associated taxa in rodent models (43)

It is likely that PPAR activation ameliorates VPA-induced hepatotoxicity through its regulation of -FAO genes, including CPT1A, CPT2 and LCAD