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The lack of vitamin B12 may result from any of the following conditions: Addisonian (pernicious) anemia this condition causes autoantibody formation against parietal cells, which results in a lack of IF essential for absorption of vitamin B12 from the intestine Malabsorption impaired absorption of vitamin B12 Gastrointestinal pathology, dysfunction, or surgery these include atrophic gastritis, celiac disease, small bowel bacterial overgrowth, pancreatic insufficiency, Helicobacter pylori infection, gastric carcinoma, and total or partial gastrectomy Diphyllobothrium latum and related species (the fish tapeworm) infestation these parasites compete with vitamin B12 for intestinal absorption

It belongs to the same broader copper-peptide area as GHK-Cu, but the peptide sequence is different, so it works best as its own reference material rather than a direct substitute

Outside of these conditions, GHK-Cu is generally well-tolerated, with minor injection site redness as the most common reported reaction

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Yes, studies indicate it may aid in healing gut wounds, reducing inflammation, and alleviating conditions like IBS