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Dietary supplements should not be used as a substitute for a varied diet

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Private clinics offering B12 injections for wellness purposes operate outside NHS prescribing guidelines, and patients should exercise caution regarding unsubstantiated health claims

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While a high-fat diet increases cholesterol secretion into the bile, which can lead to sludge and stone formation, 9 rapid weight loss and less frequent, low-fat meals also contribute to sludge and stone formation, as discussed later

Neuroinflammation and sympathetic overactivity: mechanisms and implications in hypertension