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Mechanism of Action S (GLP 1) binds and activates the GLP-1 receptor (GLP-1R), a class B G-protein-coupled receptor expressed in pancreatic beta cells, the gastrointestinal tract, the cardiovascular system, and the central nervous system

Liver-related long-term outcomes of thiazolidinedione use in persons with type 2 diabetes

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Frontiers in Clinical Diabetes and Healthcare, [online] 4

Effect of diabetes on progression of coronary atherosclerosis and arterial remodeling: a pooled analysis of 5 intravascular ultrasound trials

People in the obesity group regained about 0.5%, while those in the diabetes group lost an additional 1.3% on average, though individual outcomes varied