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If gastrointestinal discomfort (including bloating, cramps, diarrhea, or other digestive upset) or other sensitivity is experienced stop taking the product immediately

doi: 10.1155/2021/8848161 58

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Importantly, discontinuation of semaglutide after 20 weeks of treatment led to regain of body weight, whereas maintaining treatment led to continued body-weight loss over an additional 48 weeks of treatment, underlining that life-long treatment is necessary to maintain treatment effect [37]