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Brain, Behavior, and Immunity 129:757777

Understanding the Problem: In women with androgenetic alopecia, androgens like testosterone and DHT cause progressive damage to hair follicles: Androgens bind to receptors in scalp hair follicles This binding triggers follicle miniaturization follicles gradually shrink Miniaturized follicles produce thinner, shorter, weaker hair Over time, follicles may stop producing visible hair altogether This is why hair gradually becomes finer and thinner in female pattern hair loss How Spironolactone Intervenes: Step 1: Blocks Androgen Receptors Spironolactone acts as an androgen receptor antagonist it occupies the receptors that androgens would normally bind to, preventing them from triggering follicle miniaturization

GLP-1 is responsible for triggering the release of insulin and glucagon, which work together to control blood sugar

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Hashimoto's thyroiditis affects approximately 14 million Americans and increases the complexity of choosing weight loss treatments