They're all headliners
Genomic studies indicate that GHK-Cu influences the expression of over 4,000 human genes, approximately 6% of the human genome, including genes involved in DNA repair, proteasome function, oxidative stress response, and anti-inflammatory pathways
Meanwhile, Luciferase activity assays revealed no significant difference in GGCT promoter activity between Gln+ and Gln- groups, indicating that Gln does not directly regulate GGCT transcription (Fig
Also, it does not cause extrapyramidal symptoms like dystonia, Parkinsonism, akathisia
We refer to a prior review for the pharmacology of LAC [28]
Another notable strength is the ability to adjust for BMI, an important confounder that can introduce bias away from the null in this population [8, 9, 46]