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The liposome-water distribution ratio is a more suitable descriptor of the uptake of hydrophobic ionizable compounds into biological membranes than the corresponding octanol-water distribution ratio 33

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There was limited density for the conjugated lipid, which could only be resolved in high-resolution receptor-focused maps of Cagri-AMY 1 R-G s and Cagri-CTR-G s structures, albeit modelling was restricted to the Glu linker and an adjacent short segment of the fatty diacid as the remainder of the modification was not resolved

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doi: 10.1111/adb.12295 [DOI] [PMC free article] [PubMed] [Google Scholar] van Bloemendaal L, IJzerman RG, Ten Kulve JS, Barkhof F, Konrad RJ, Drent ML, Veltman DJ, Diamant M