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There are GLP-1 receptors in the brain that when stimulated result in a decrease in appetite

[PubMed: 3818895] 277

The supplements dont appear to have elicited legal concern from GLP-1 drugmakers, but that could change if the products become competitors, said Claudia Lewis, co-chair of Venable LLPs FDA group

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7 This is crucial as psoriasis is associated with an increased risk of cardiovascular events 8 and a patient may be taking medications that are metabolised by CYP/P-glycoprotein mechanisms