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doi: 10.1001/jama.2024.3073 Summary Keywords obesity, obesity pharmacotherapy, precision medicine, personalized treatment, combination therapy, weight management, weight loss Citation Steenackers N, Toumassian J, Deleus E, Mertens A, Lannoo M, Pazmino S, van Laar ADE, Van der Schueren B and Vangoitsenhoven R (2025) Pharmacotherapy for obesity: are we ready to select, tailor and combine pharmacotherapy to achieve more ambitious goals