Needle size matters because it decides which layer of tissue the B12 reaches, how comfortable the injection is, and how cleanly it goes in
Injuries such as sciatic nerve damage, shoulder injury related to vaccine administration (SIRVA), and localized tissue necrosis are often preventableyet they continue to occur due to poor technique, inadequate training, or improper site selection
PubMed 22962027 TB-4 Phase 1 human safety first-in-human randomized, double-blind, single- and multiple-dose Phase 1 of recombinant human thymosin 4 in healthy volunteers, no serious adverse events: PubMed 34346165
Do not take other forms of B12 while undergoing injections to prevent overdose
Narsinh KH, Hui F, Saloner D, et al
Intramuscular shots can be more painful and more likely to bruise