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Several alternatives are available, such as: Other SSRIs and SNRIs (such as escitalopram, fluoxetine, venlafaxine, and duloxetine) also work by targeting serotonin (and some norepinephrine)

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The Substance Abuse and Mental Health Services Administration (SAMHSA) warns that self-medicating pain with alcohol significantly increases the risk of developing both alcohol use disorder and chronic pain conditions

Besides neurons, astrocytes and microglia express GLP-1Rs (see Vrang and Larsen, 2010 for a general overview) (Merchenthaler et al., 1999