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You inject it subcutaneously, typically in the abdomen, thigh, or upper arm, once per week

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It then divides the target dose by that concentration to calculate the required volume

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doi: 10.1097/gme.0b013e318240f6f3 [DOI] [PubMed] [Google Scholar] 45.Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM

Theoretically, the accumulation of unfolded proteins in the ER can cause ER stress and lead to unfolded protein response 44