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AMPK activation suppresses key fibrotic signalling pathways, including TGF-/Smad and NFB, resulting in inhibition of fibroblast proliferation and reduced ECM protein production [19]

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Combined with Usnea Barbata and Pulsatilla Koreana, these three extracts are claimed to form a natural preservative system that also has anti-inflammatory effects and might help with skin conditions such as blemishes, atopic dermatitis, and dandruff

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Demographics and baseline characteristics by trial and baseline eGFR in (A) SUSTAIN 4 and 5, (B) SUSTAIN 6 and 10, and (C) PIONEER 5 and 6