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The authors of one trial (95) included in the above-mentioned meta-analysis (89) noted that little cognitive decline was observed in the placebo group over their two-year trial, which may have limited their power to detect an effect of the B-vitamin intervention (95)

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This offers a more convenient option for patients who prefer to avoid injections, while still supporting metabolic pathways under medical guidance

Clinical pen device: In trials, cagrilintide was delivered via Novo Nordisk's prefilled pen

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