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In subjects with renal impairment including end-stage renal disease (ESRD), no change in tirzepatide pharmacokinetics (PK) was observed [see Clinical Pharmacology (12.3)]

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For example, a brand name product in Italy, with Italian language labelling, can be sold to the UK, and this product must be re-labeled in English in order to be made available for sale in England

Efficacy and safety of cagrilintide with semaglutide in type 2 diabetes