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Meng, L., Gan, S., Zhou, Y., Cheng, Y., Ding, Y., Tong, X., et al

Nature 377 , 239242 (1995)

Thus, more prospective clinical studies on non-diabetic obese patients are needed

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Consequently, suppressing the MVA pathway can downregulate GPX4 activity and induce ferroptosis ( Lipid peroxidation Fatty acids serve as vital cellular nutrients and also maintain a wide range of cellular functions, including the formation of cellular membranes and the transmission of cellular signals ( de novo fatty acid synthesis (Yuan et al., 2016)