Tirzepatide is FDA-approved for type 2 diabetes (as Mounjaro) and for obesity (as Zepbound)
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Various general autoantibodies have also been identified in ME/CFS, such as those against cellular components including anchorage molecules (514), HSP-60 (515), microtubule associated protein 2 (516), cardiolipin in 92-95% of ME/CFS patients in two studies (509, 510) but only 4% in another study (506), and neo-antigens (517)
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Clinically, this localized oxidative damage in the brain translates into the severe cognitive dysfunction, memory impairment, sensory overload, and profound "brain fog" that so many patients with chronic neuroimmune conditions endure daily
