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Blood 90 : 111

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It is known to exacerbate inflammation and redox imbalances (251) by triggering the NLR family pyrin domain containing 3 (NLRP3) inflammasome (251), increasing the release of inflammatory cytokines such as IL-1 and IL-18 (376)

The peptide demonstrates protective effects against gastric ulceration, promotes healing of intestinal lesions, and modulates gut inflammation through multiple pathways

Compared with targeted drugs, traditional Chinese medicine has the characteristics of multiple targets and can regulate a variety of signal pathways, such as regulating ADAMTS18, ROS, Nrf2, GPX4 and other molecules, so as to regulate ferroptosis