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Based on the efficacy and safety records in T2DM, attention has been given to the repurposing of metformin as part of adjunct therapy for the treatment of cancer, age-related diseases, inflammatory diseases and COVID-19

Glutamine, glycine, aspartate, 10-formyl THF, and CO 2 are used as substrates for the synthesis of inosine monophosphate (IMP)the intermediate product of AMP and GMP (Figure 1)

doi: 10.1136/jnnp.72.5.567 47 SaedisomeoliaAAshooriM

Strohmaier, H

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The immunological and genetic basis of inflammatory bowel disease