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Contraindications include personal or family history of medullary thyroid carcinoma, Multiple Endocrine Neoplasia syndrome type 2, and severe gastroparesis
the crude HR for hip fracture with GLP-1 RAs compared to DPP-4is was 0.68 [0.490.96], which was unaltered in the fully adjusted model (HR 0.65 [0.460.93])
Retatrutide dosing protocols are still being refined, but early data supports extended treatment courses with careful dose optimization
The manufacturer, Eli Lilly, is enrolling patients with type 2 diabetes to compare the effect of retatrutide with semaglutide in adult patients with type 2 diabetes and poor glycemic control with metformin and with or without SGLT2 inhibitors
Collagen is the protein responsible for giving skin its firmness and elasticity
10.1016/j.peptides.2015.02.007 Peptides 129 PedersenJ.UgleholdtR
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