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FPN caused hippocampal microglia and astrocytes to proliferate and become more active, potentially increasing inflammatory cytokine expression 14 , such as IL-6, TNF- , and IL-1 , which could exacerbate oxidative stress and inflammation 3

They stated that this could penalize innovative therapies, favor older and lower-cost alternatives, and ultimately limit patient access to more effective technologies

(19) Cystic fibrosis leads to suppressed glutathione levels and the impaired ability to produce more at a normal rate

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Prior research has demonstrated that insufficient GSH is associated with cellular damage and neuron death in the enteric nervous system