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The authors speculate that the reduced activity of the redox-sensitive protein tyrosine phosphatase (PTP)1B and the higher concentration of irreversible oxidized PTP1B could be, at least in part, responsible for this effect [12]

Stem Cells 36:11381145 Weiskopf K, Schnorr PJ, Pang WW et al (2016) Myeloid cell origins, differentiation, and clinical implications

A shift toward green or teal suggests copper dissociation or pH changes affecting the complex

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In older adults with compromised cardiac or renal function, this can precipitate oedema or exacerbate hypertension

Neuroscience 146 : 962973