semaglutide oral cardiovascular indication 2025 news ACC 2025: Reduces Events by 14% at 4 Years SOUL trial shows oral semaglutide

The branded injectable GLP-1 products are separate FDA-approved drugs produced by their manufacturers

Rieder notes, there is a little bit of data showing that medications, like semaglutide, may actually help to prevent certain addictive behaviors in studies of rats. A greater worry voiced by physicians is that semaglutide is being doled out to thin patients who dont need it, which depletes the supply for those who actually do

According to clinical studies, those who took semaglutide therapy typically dropped 1525% of their body weight over 68 weeks, and this weight loss was maintained over a longer period, demonstrating that it can be a long-term solution for weight management

Changes in bowel movements are also common

Gentle rolling is sufficient

Other causes could be at play, especially if youve been on the same dose for a while and are just now noticing this symptom