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Studies show that yerba mate may interact with the muscle relaxant Zanaflex or the antidepressant Luvox

JAMA Internal Medicine 2008, 168: 1310-1316

Scheibe and Dietz 2012

A1: Generally we don't provide free sample, but we can return sample cost when the buyer place the bulk order

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Dalkara T, Endres M, Moskowitz MA