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Think density, not quantity

We see penetration would be much greater under this scenario, given that the orals would likely have less of the side effects (nausea, vomiting, diarrhea, constipation, lack of desire to eat any food) or even a monthly injectable (to decrease injection fear burden)

Cardiotoxicity can appear soon after or long after chemotherapy, and may vary from subclinical heart muscle dysfunction to heart failure (Stewart 2010

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These individuals lost 15 percent to nearly a third of their body weight over 68 weeks

They should not be used during pregnancy and require discontinuation at least 2 months (semaglutide) or 1 month (tirzepatide) before a planned pregnancy