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In 2024, the five leading GLP-1s generated $46.1 billion, surpassing Keytrudas $29.5 billion by $16.6 billion, and topping the combined $41.2 billion from those two oncological therapies

The trial also identified a dose-related dysesthesia (nerve-tingling) signal in 8.8% of 9 mg and 20.9% of 12 mg patients a safety signal that doesn't appear in the cagrilintide literature

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