There are a few options: break it up with an endoscopic knife or use medications like metoclopramide or erythromycin to chemically get things moving
Koehler JA, Baggio LL, Lamont BJ, Ali S, and Drucker DJ
March 31st, 2026 5 min read For people whove struggled for years with excessive weight, GLP-1s are a paradigm shift
They set up a policy where compounders could work around FDA approval guidelines in cases of shortages. But right now, there is no shortage of GLP-1 medications, and because companies like Eli Lilly and Novo Nordisk have patents, patients are likely years away from FDA-approved generics
Limited preclinical research has explored potential interactions between GLP-1 signaling and stress hormone pathways
Diabetol Int 17 , 37 (2026)