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By evaluating the controlled release of IGF-I from a biodegradable (PEG)ylated fibrin gel matrix and the subsequent recovery of skeletal muscle from I/R[66], they showed that PEG-IGF-I treatment resulted in significant improvement of muscle function and structure

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It's also worth noting that the potential immunological benefits may not require the doses associated with significant weight loss, and therefore come with less side effects (12)

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Always check with a healthcare provider before combining semaglutide with other medications, as interactions can impact its effectiveness and safety

Hall et al., 2020)