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A careful skeptic would say: the in-clinic procedure has solid evidence, the at-home extension is biologically plausible and consistent with the procedure, but the dataset is younger than the recommendation implies

This happens through increased activity of enzymes (creatine kinase, lactate dehydrogenase, aspartate aminotransferase, alanine aminotransferase)

Purified recombinant protein (3 g) was resolved using 18% w/v SDS-PAGE in reduced (+-mercaptothanol, R) and non-reduced (NR) conditions and stained with Coomassie Brilliant Blue R250

References Lintner K, Peschard O

Mistreat it during reconstitution and it unfolds

If you do tear or cut the patch, dont use it