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Aleniglipron is an oral, small-molecule drug in development for treating obesity
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Cerebrolysin is one of the most extensively studied neuropeptide preparations in clinical medicine, with research focused on neuroprotection, memory, and recovery from neurological conditions
But what they found instead was the following (quoting from the trial result) In pre-specified analyses for time to first occurrence of MACE, there were 44 MACE-5 (all-cause death, heart attack, stroke, heart failure event, or coronary revascularization ) events observed in participants randomized to retatrutide (pooled 9 mg and 12 mg) and 52 events observed in those randomized to placebo, resulting in a hazard ratio of 0.82 (95.0% CI: 0.55 to 1.22)
4 The effect is more consistent under physiological stress, particularly sleep deprivation
