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After draining, TSQ (50 M, SigmaAldrich, SML2656) was added and incubated for 30 min

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Despite lack of statistically significant outcome, 42.0% of patients treated with obexelimab (21/50) showed improvement compared to 28.6% on placebo (12/42) (P = 0.183)

Orbital fibroblasts may be activated by these antibodies, leading to proliferation of fibroblasts and differentiation to adipocytes