After recognition and internalization of the ACs, the phagosome containing the apoptotic cargo undergoes a maturation process mediated by the activity of VPS34 [14], phosphatidylinositol-3-phosphate, and Rab proteins, followed by the fusion of the late phagosome with the lysosome
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Baicalin offers a potentially safer alternative to synthetic JAK inhibitors, although challenges remain regarding solubility, extraction standardization, and the lack of robust clinical validation [45]
Cell lines IMR90 (human, American Type Culture Collection (ATCC) CCL-186), SK-MEL-103 (ATCC, HTB-69), A549 (ATCC, CCL-185), MCF7 (ATCC, HTB-22) and PC3 (ATCC, CRL-1435) cells were obtained from the ATCC
(2021) 16:e0248777