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Experiments were performed from 2 weeks after tamoxifen administration

BMJ 384, e076410

Miyawaki, A

It is also strongly pro-angiogenic: in rat and endothelial-cell models it promoted new blood-vessel formation and blood-flow recovery by up-regulating the VEGFR2AkteNOS pathway[2]

By contrast, tumor suppressive miRNAs prevent tumors from developing by negatively regulating oncogenes and/or genes controlling proliferation or apoptosis

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