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Bostom AG, Jacques PF, Nadeau MR, Williams RR, Ellison RC, and Selhub J (1995a)

A potential mechanism for the greater weight reduction associated with tirzepatide versus semaglutide treatment may be that while both drugs are GLP1 receptor agonists, tirzepatide also activates GIP receptors

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J Cell Physiol 232(5):913921

The slightly lower risk of self-harm among GLP-1 users was an unexpected finding that might warrant further investigation