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Esta dosis inicial no es teraputica, sino que sirve para mejorar la tolerabilidad gastrointestinal

Tosatto SC, Bosello V, Fogolari F, Mauri P, Roveri A, Toppo S et al

Zepbound was launched by Lilly after the success of Mounjaro, the company's other form of tirzepatide, which is aimed at curbing diabetes

However, in a murine model, knockout of glucagon genes originating from the bowel elicited no increase in food intake, and thus appetite suppression is attributed to GLP-1 produced within the CNS [112]