When a week feels like nothing is happening, the rest of the timeline often shows what actually changed even if the scale did not move that week
To illustrate, studies show that as much as two-thirds of the weight lost during GLP-1 therapy can be regained within a year of stopping the medication (Old et al., 2025)
Nature Reviews Cardiology , 20 (7), 463-474
Some conditions that require precaution include: Diabetic Retinopathy: In clinical trials, it was observed that brand-name semaglutide can temporarily worsen eye problems in diabetic patients due to sudden hypoglycemia (drops in blood glucose levels), which can worsen diabetic retinopathy
The regulatory pathway for nasal peptide delivery is well-established through precedents like desmopressin and calcitonin nasal sprays
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