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Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE

To the best of our knowledge, this study is the first study of its kind that was conducted to investigate the effects of the L-carnitine supplement on frailty status either among the frail or prefrail elderly

Tetrandrine can enhance the ubiquitination and degradation of spleen tyrosine kinase (Syk) through AhR/non-receptor tyrosine kinase/c-Cbl signaling pathway and regulate the expression of Syk and phospholipase-C, thereby inhibiting osteoclastogenesis and bone destruction in arthritis (90, 91)

Metabolic regulation of chromatin modifications and gene expression

In addition, 83.3% of GT4a (n = 6) and 75% of GT4d (n = 4) infected patients for which we have information on transmission risk were PWIDs